化学性质：                                                                                                             

产品描述：                                                                                                            

Kynurenic acid is a natural metabolite of tryptophan via the kynurenine pathway. It has pronounced effects on neuronal signaling and, thus, impacts diverse neurological systems. [1] [2] Kynurenic acid broadly antagonizes ionotopic glutamate receptors at high micromolar to millimolar concentrations and is used to pharmacologically block the activation of these receptors in vivo or in vitro.[3]  In addition, it reportedly has more potent effects at glutamate receptor subunit ζ-1 (Ki = 5.4 &#181M), GPR35 (EC50 = 39 &#181M), aryl hydrocarbon receptor (EC50 = 300 nM), and neuronal acetylcholine receptor α-7 (IC50 = 7 &#181M). [4] [5][2] [6]

特别提醒：