化学性质:
规格 | 500μg 1mg 5mg |
CAS | 1111-39-3 |
别名 | N/A |
化学名 | N/A |
分子式 | C43H66O14 |
分子量 | 807 |
溶解度 | Chloroform: Slightly Soluble,DMSO: Slightly Soluble,Methanol: Slightly Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes. This inhibition results in loss of the transmembrane Na+ gradient, which decreases activity of the Na+/Ca2+ exchanger, increasing intracellular calcium levels, inotropy, and cardiac force. Formulations containing acetyldigitoxin have been used for the treatment of heart failure and chronic atrial fibrillation.
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