化学性质:
规格 | 10mg 50mg |
CAS | 1401242-74-7 |
别名 |
|
化学名 | (R,Z)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carbimidic acid |
分子式 | C23H25N3O4S2 |
分子量 | 471.59 |
溶解度 | DMSO: 5 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM.IC50 value: 270 nM (EC50) [1]Target: K(v)7.1 activatorML277 was shown to be highly selective against other KCNQ channels (>100-fold selectivity versus KCNQ2 and KCNQ4) as well as against the distantly related hERG potassium channel.
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