化学性质:
规格 | 10mg 50mg |
CAS | 119431-25-3 |
别名 |
|
化学名 | (R)-1-(4-chlorophenyl)-2-(4-(4-fluorobenzyl)piperidin-1-yl)ethanol |
分子式 | C20H23ClFNO |
分子量 | 347.86 |
溶解度 | DMF: 10mg/mL,DMSO: 2mg/mL,Ethanol: 2mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM).IC50 value:Target: NR2B-NMDA antagonistHuman N-type Ca2+ channel currents were inhibited by ifenprodil and eliprodil with IC50 values of 50 microM and 10 microM respectively whereas P-type Ca2+ channel currents were inhibited reversibly by ifenprodil and eliprodil with approximate IC50 values of 60 microM and 9 microM respectively. eliprodil (1 microm) produced a moderate reverse rate-dependent prolongation of the action potential duration (7.4+/-1.5, 8.9+/-2.1 and 9.9+/-1.8% at cycle lengths of 300, 1000 and 5000 ms, respectively; n=9).
特别提醒:
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标签:Eliprodil
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