化学性质:
规格 | 10 mg 50 mg |
CAS | 191744-13-5 |
别名 | N/A |
化学名 | N/A |
分子式 | C13H13NO4 |
分子量 | 247.25 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
AMPAkine; positive allosteric modulator of AMPA. Prototypical benzamide which occupies subsite A only. Modulates channel deactivation and desensitization.
Harms et al (2013) Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology 64 45 PMID:22735771 |Timm et al (2011) Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol. 80 267 PMID:21543522 |Hennegriff et al (1997) Stable expression of recombinant AMPA receptor subunits: binding affinities and effects of allosteric modulators. J.Neurochem. 68 2424 PMID:9166736
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