化学性质:
规格 | 10mM (in 1mL DMSO) 100mg |
CAS | 154235-83-3 |
别名 | CX516; BDP 12; Ampakine CX516 |
化学名 | piperidin-1-yl(quinoxalin-6-yl)methanone |
分子式 | C14H15N3O |
分子量 | 241.29 |
溶解度 | ≥ 13.45 mg/mL in DMSO, ≥ 92 mg/mL in EtOH, ≥ 24.1 mg/mL in H2O with gentle warming |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). IC50 value: Target: AMPA receptorAmpalex ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation. Researches suggest that AMPA receptors may be potential pharmaceutical targets for the treatment of neurodegenerative diseases, and highlights AMPAkines, in particular, as possible therapeutic agents.
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标签:Ampalex
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