化学性质:
规格 | 500μg 1mg 5mg |
CAS | 88899-55-2 |
别名 | NSC 381866 |
化学名 | (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one |
分子式 | C35H58O9 |
分子量 | 622.84 |
溶解度 | 5 mg/ml in DMSO or in menthanol |
储存条件 | Desiccate at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Bafilomycin A1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases), blocking these proton pumps in mammalian, plant, or fungal cells with an IC50 value in the 4-400 nM range.[1] It is at least 1,000-fold less potent at most other types of ATPases.[1] Bafilomycin A1 also inhibits autophagy by preventing vacuolar acidification necessary for autophagosome maturation.[2],[3]
特别提醒:
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标签:Bafilomycin A1
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