GLPG1837CS-01Y73926_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	1mg 5mg 10mg 50mg 100mg
CAS	1654725-02-6
别名	N/A
化学名	N/A
分子式	C16H20N4O3S
分子量	348.42
溶解度	DMSO : ≥ 250 mg/mL (717.52 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.

GLPG1837 is a potent CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively. GLPG1837 increases the conductivity of the G551D CFTR channel with obtained potency of 181 nM[1]. GLPG1837 is reversible CFTR potentiator, with a the apparent affinity within a range of 0.2∼2 uM[2].

特别提醒：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：GLPG1837

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抑制剂 > 泛素化/蛋白酶体 > GLPG1837

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