化学性质:
规格 | 5mg 10mg 50mg 100mg |
CAS | 1798331-92-6 |
别名 | N/A |
化学名 | N/A |
分子式 | C16H13ClN2O2 |
分子量 | 300.74 |
溶解度 | DMSO : ≥ 64 mg/mL (212.81 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
QX77 is a chaperone-mediated autophagy (CMA) activator.
Treatment with CMA activator QX77 rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells. QX77 treatment also increases LAMP2A localization at the lysosomal membrane[1].
[1]. Zhang J, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017 Jun 23;292(25):10328-10346.
特别提醒:
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2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
标签:QX77
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