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抑制剂 > 泛素化/蛋白酶体 > Prazosin HCl
产品名称:
Prazosin HCl
型号:
CS-01Y73903
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

10mM (in 1mL DMSO) 100mg 200mg 500mg

CAS

19237-84-4

别名

N/A

化学名

[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone;hydrochloride

分子式

C19H21N5O4.HCl

分子量

419.86

溶解度

7mg/mL in DMSO

储存条件

Store at -20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                            

Prazosin hydrochloride is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder.Target: Adrenergic ReceptorPrazosin hydrochloride, is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, andpanic disorder. It is an alpha-adrenergic blocker that is specific for the alpha-1 receptors. These receptors are found on vascular smooth muscle, where they are responsible for the vasoconstrictive action of norepinephrine. They are also found throughout the central nervous system. As of 2013, Prazosin (hydrochloride) is off-patent in the US, and the FDA has approved at least one generic manufacturer.In addition to its alpha-blocking activity, Prazosin (hydrochloride) is an antagonist of the MT3 receptor (which is not present in humans), with selectivity for this receptor over the MT1 and MT2 receptors.Prazosin hydrochloride is orally active and has a minimal effect on cardiac function due to its alpha-1 receptor selectivity. However, when Prazosin (hydrochloride) is initially started, heart rate and contractility go up in order to maintain the pre-treatment blood pressures because the body has reached homeostasis at its abnormally high blood pressure. The blood pressure lowering effect becomes apparent when Prazosin (hydrochloride) is taken for longer periods of time. The heart rate and contractility go back down over time and blood pressure decreases.

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签:Prazosin HCl 

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