化学性质:
规格 | 10mM (in 1mL DMSO) 5mg 10mg 50mg |
CAS | 1152311-62-0 |
别名 |
|
化学名 | 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide |
分子式 | C26H27F3N2O6 |
分子量 | 520.5 |
溶解度 | ≥ 21.8mg/mL in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
VX-661, one of vertex derivatives, corrects F508del-CFTR trafficking and increases F508del-CFTR protein activity in vitro [1].
VX-661 treated alone or in combination with ivacaftor have shown to enhance F508del-CFTR trafcking to the cell surface. VX-661 has been at phase 2 study [1].
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标签:VX-661
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