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抑制剂 > 细胞周期/检查点 > MLS-573151
产品名称:
MLS-573151
型号:
CS-01Y73622
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

5 mg 10 mg 25 mg 50 mg 100 mg

CAS

10179-57-4

别名

 

化学名

4-(4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-benzenesulfonamide

分子式

C21H19N3O2S

分子量

377.5

溶解度

20mg/ml in DMSO;30mg/ml in dimethyl formamide

储存条件

Store at -20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                            

MLS-573151 is a specific and cell permeable inhibitor of Cdc42 [1].

Cdc42 is a small GTPase of the Rho family involved in regulating signaling pathways that control diverse cellular functions such as cell morphology, cell migration, cell cycle progression and endocytosis [2].

In vitro: MLS-573151 was a specific, cell permeable inhibitor of Cdc42 with an IC50 of 2 μM [1]. MLS-573151 showed no effect on other GTPases, including the related Rho family members RhoA, Rac1, and Rac2. MLS-573151 functioned by blocking the binding of GTP to Cdc42 [1]. In marrow-derived mesenchymal stem cells, MLS-573151 showed no effect on cell migration [3].

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签:MLS-573151 

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