PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)CS-01Y73580

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一、概述：

化学性质：

规格	100μg 500μg 1mg 5mg
CAS	1628353-02-5
别名	N/A
化学名	N/A
分子式	C41H78O22P4•4Na
分子量	1138.9
溶解度	CHCl3:CH3OH:H2O (2.5:3:1): 3.8 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references and .

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标签：PtdIns-(3 4 5)-P3 (1 2-dipalmitoyl)

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