化学性质:
规格 | 5mg 10mg 50mg 100mg |
CAS | 672926-32-8 |
别名 |
|
化学名 | (S,Z)-N-(5-(ethoxycarbonyl)-4-methylthiazol-2-yl)-2-(2-hydroxy-4-oxoquinazolin-3(4H)-yl)-3-methylbutanimidic acid |
分子式 | C20H22N4O5S |
分子量 | 430.48 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Kif15-IN-1, a potent Kif15 kinesin inhibitor; inhibits cellular proliferation in various tumor cell lines [1].
Kif15,also known as Kinesin-12 and HKLP2, is a motor protein expressed in all cells during mitosis and in postmitotic neurons undergoing axon growth [2]. Kif15 is a kinesin-related protein whose mitotic homologues are believed to crosslink and immobilize spindle microtubules.KIF15 is involved in maintaining bipolar microtubulespindle apparatusin dividing cells and shares redundant functions with KIF11 [3].
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标签:Kif15-IN-1
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