Gly-Arg-AMC (hydrochloride)CS-01Y73549_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	1mg 5mg 10mg 25mg
CAS	70274-78-1
别名	N/A
化学名	N/A
分子式	C18H24N6O4.XHCl
分子量	388.4
溶解度	DMF: 30mg/mL,DMSO: 30mg/mL,DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL,Ethanol: 20mg/mL
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

|1. Rubach, J.K., Cui, G., Schneck, J.L., et al. The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis. Biochemistry 51(38), 7551-7568 (2012).

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标签：Gly-Arg-AMC (hydrochloride)

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