PF 3758309 dihydrochlorideCS-01Y73481_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	10 mg 50 mg
CAS	N/A
别名	N/A
化学名	N/A
分子式	C25H30N8OS.2HCl
分子量	563.55
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Potent PAK4 inhibitor (IC50 = 1.3 nM; Kd = 2.7 nM). Inhibits proliferation and anchorage-independent growth of a panel of tumor cell lines in vitro. Suppresses growth of human HCT116 and A549 tumor cell xenografts in mice. Orally available.

Murray et al (2010) Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth. Proc.Natl.Acad.Sci.U.S.A. 107 9446 PMID:20439741

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标签：PF 3758309 dihydrochloride

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抑制剂 > 细胞周期/检查点 > PF 3758309 dihydrochloride

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