LCB 03-0110 dihydrochlorideCS-01Y73465_上海莼试生物技术有限公司

产品详情

一、概述：

化学性质：

规格	10 mg 50 mg
CAS	N/A
别名	N/A
化学名	N/A
分子式	C24H23N3O2S.2HCl
分子量	490.45
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Potent c-Src kinase inhibitor (IC50 = 1.3 nM). Also potent inhibitor of discoidin domain receptor 2 (DDR2) family tyrosine kinases, BTK and Syk. Suppresses LPS-induced activation of macrophages and TGF-β1- induced activation of fibroblasts in vitro. Also inhibits activation of macrophages and fibroblasts and suppresses scar formation in a wound healing model.

Sun et al (2012) LCB 03-0110, a novel pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor, suppresses scar formation by inhibiting fibroblast and macrophage activation. J.Pharmacol.Exp.Ther. 340 510 PMID:22128347

特别提醒：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：LCB 03-0110 dihydrochloride

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