上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 1 mg |
| CAS | N/A |
| 别名 | N/A |
| 化学名 | N/A |
| 分子式 | C100H179N45O25 |
| 分子量 | 2411.8 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen species (ROS) production in vitro. Reduces programmed cell death and improves cell viability by protecting mitochondrial integrity. Reduces mitochondrial fragmentation and mitochondrial ROS production in mouse model of Parkinson's disease. Cell permeable.
Qi et al (2013) A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. J.Cell Sci. 126 789 PMID:23239023 |Filichia et al (2016) Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. Sci.Rep. 13 32656 PMID:27619562
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：P110
联系人：高小姐
手 机：13585831301
Q Q：3004967995
座 机：021-59541103
传 真：021-60443211
地 址：上海嘉定区嘉罗公路1661
