上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 500μg 1mg 5mg 10mg |
| CAS | 143492-38-0 |
| 别名 | N/A |
| 化学名 | N/A |
| 分子式 | C23H39NO2 |
| 分子量 | 361.6 |
| 溶解度 | DMF: 20 mg/ml,DMSO: .1 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2) (1:2): .5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 µM; IC50 = 1-5 µM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 µM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 µM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner.
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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