化学性质:
规格 | 1mg 5mg 10mg 25mg |
CAS | 496864-15-4 |
别名 | N/A |
化学名 | 7-butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine |
分子式 | C17H19N3O |
分子量 | 281.4 |
溶解度 | DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 12 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Aloisine is an inhibitor of Cdk1/cyclin B, Cdk5/p25, and GSK3 (IC50s = 0.70, 1.5, and 0.92 uM, respectively). It is a derivative of the aloisines A and B, which competitively inhibit ATP binding to the catalytic subunit of CDKs and GSKs.
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