化学性质:
规格 | 500μg 1mg 5mg |
CAS | 14 |
别名 | Ins(1,4,5)P3 |
化学名 | D-myo-inositol-1,4,5-tris(hydrogen phosphate), trisodium salt |
分子式 | C6H12O15P3•3Na |
分子量 | 486 |
溶解度 | 50mg/mL in PBS, pH 7.2 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate.[1][2] It binds to one of several Ins(1,4,5)P3 receptors, each containing a calcium channel domain. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium.[2][3]
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