Chroman 1 (hydrochloride hydrate)CS-01Y73351_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	1 mg 5 mg 10 mg
CAS	N/A
别名	N/A
化学名	N/A
分子式	C24H28N4O4·2HCl [XH2O]
分子量	527.4
溶解度	DMSO: 100 mM,Water: 5 mM
储存条件	-20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Chroman 1 is an inhibitor of Rho-associated kinase 2 (ROCK2; IC50 = <1 nM).1 It is selective for ROCK2 over protein kinase A (PKA) and Cdc42-binding kinase (MRCKα; IC50s = 1,740 and 127 nM, respectively). Chroman 1 inhibits phosphorylation of myosin light chain (MLC) in a cell-based assay (IC50 = <4 nM).

1.Chen, Y.T., Vojkovsky, T., Fang, X., et al.Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitorsMed. Chem. Commun.2(1)73-75(2011)

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1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：Chroman 1 (hydrochloride hydrate)

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