上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 1 g 5 g 10 g |
| CAS | 214360-73-3 |
| 别名 | N/A |
| 化学名 | N/A |
| 分子式 | C12H18BNO2 |
| 分子量 | 219.1 |
| 溶解度 | DMF: 20mg/mL,DMF:PBS (pH 7.2) (1:5): 0.16mg/mL,DMSO: 10mg/mL,Ethanol: 3mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline is a heterocyclic building block.1,2 It has been used in the synthesis of 3-aminoindazole-based multi-targeted receptor tyrosine kinase (RTK) inhibitors with anticancer activity and roscovitine derivatives that are dual inhibitors of cyclin-dependent kinases (CDKs) and casein kinase 1 (CK1).
1.Dai, Y., Hartandi, K., Ji, Z., et al.Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based orally active multitargeted receptor tyrosine kinase inhibitorJ. Med. Chem.50(7)1584-1597(2007) 2.Paraiso, K.H.T., Haarberg, H.E., Wood, E., et al.The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanismsClin. Cancer Res.18(9)2502-2514(2012)
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：4-(4 4 5 5-Tetramethyl-1 3
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