上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 1g 5g |
| CAS | 32703-82-5 |
| 别名 | N/A |
| 化学名 | N/A |
| 分子式 | C16H14N2 |
| 分子量 | 234.3 |
| 溶解度 | Chloroform: 10 mg/ml,DMF: 1 mg/ml,DMF:PBS (pH 7.2) (1:2): 0.33 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
BRD9876 is an inhibitor of the kinesin spindle protein Eg5.1 It arrests Eg5-mediated microtubule gliding, as well as inhibits Eg5 ATPase activity in the presence of microtubules, in cell-free assays. BRD9876 is cytotoxic to MM.1S stroma-independent multiple myeloma cells (IC50 = 2.2 µM). It induces cell cycle arrest at the G2/M phase in MM.1S cells when used at a concentration of 10 µM.
1.Chattopadhyay, S., Stewart, A.L., Mukherjee, S., et al.Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitorsCell Rep.10(5)755-770(2015)
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：BRD9876
联系人：高小姐
手 机：13585831301
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座 机：021-59541103
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