化学性质:
规格 | 5 mg 10 mg 25 mg 50 mg |
CAS | 2170848-99-2 |
别名 | N/A |
化学名 | N/A |
分子式 | C10H6BFNa2O5 |
分子量 | 281.94 |
溶解度 | N/A |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
QPX7728-OH disodium (compound 13) is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 13. QPX7728-OH disodium inhibits cleavage of Nitrocefin by purified class A, C and D enzymes, with Kis less than 0.1 μμ[1].
QPX7728-OH disodium potentiates Aztreonam and Tigemonam against strains expressing class A and class C enzymes, with MICs≤5 μg/mL. QPX7728-OH disodium potentiates Biapenem against strains expressing class A (KPC) or class D (OXA-48) carbapenemases, with MICs≤5 μg/mL[1].
[1]. Scott Hecker, et al. Boronic acid derivatives and therapeutic uses thereof. WO2018005662A1..
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