Fosravuconazole L-lysine ethanolateCS-01Y72624_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	5 mg 10 mg 25 mg 50 mg 100 mg
CAS	914361-45-8
别名	N/A
化学名	N/A
分子式	C31H40F2N7O8PS
分子量	739.73
溶解度	DMSO : 50 mg/mL (67.59 mM; Need ultrasonic)\|H2O : < 0.1 mg/mL (ultrasonic) (insoluble)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a prodrug of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used for candidiasis, onychomycosis and parasitemia research[1][2][3].

Fosravuconazole has potent in vitro antifungal activity against a wide range of fungal species, including Candida, Aspergillus, and Trichophyton species[1].

Fosravuconazole (E-1224; 10-50 mg/kg; oral administration; daily; for 20 days) treatment suppresses the parasitemia and prevents death in mice infected with the T. cruzi Y strain[3].

[1]. Shinichi Watanabe, et al. Efficacy and safety of fosravuconazole L-lysine ethanolate, a novel oral triazole antifungal agent, for the treatment of onychomycosis: A multicenter, double-blind, randomized phase III study. J Dermatol. 2018 Oct;45(10):1151-1159.

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标签：Fosravuconazole L-lysine ethanolate

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