化学性质:
规格 | 10mM * 1 mL in DMSO 5mg 10mg 50mg |
CAS | 11078-21-0 |
别名 | N/A |
化学名 | N/A |
分子式 | C35H58O11 (for Filipin III) |
分子量 | 654.8 |
溶解度 | DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble |
储存条件 | Store at -20°C; solution was used in half a month |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Filipin complex is a neutral polyene originally isolated from S. filipinensis with antifungal activity. It inhibits cell growth as well as mitochondrial terminal electron transport in S. cerevisiae when used at a concentration of 135 ug/ml. Filipin complex binds to various sterols, particularly 24α-methyl cholesterol 24α-ethyl cholesterol, and cholesterol, in aqueous solutions and in fungal cell membranes when used at a concentration of 50 ug/ml, inducing membrane pit formation and leakage of cell contents. It is a fluorescent compound that has been used to label sterols within biological structures for imaging. Filipin complex displays excitation/emission maxima of 338/480 nm, respectively.
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