NGI-1 (ML414)CS-01Y72472_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	10mM*1mLinDMSO 5mg 10mg 50mg 100mg
CAS	790702-57-7
别名	N/A
化学名	N/A
分子式	C17H22N4O3S2
分子量	394.51
溶解度	DMSO : 160 mg/mL (405.57 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

描述：

NGI-1 is a cell permeable inhibitor.

NGI-1 blocks EGFR N-linked glycosylation in lung adenocarcinoma cells as assessed. In controls EGFR is biotinylated, consistent with its plasma membrane expression, but in NGI-1 treated cells the EGFR is predominantly found in the non-biotinylated intracellular fraction suggesting a change in cellular localization[1].

[1]. Lopez-Sambrooks C, et al. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nat Chem Biol. 2016 Dec;12(12):1023-1030.

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1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

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标签：NGI-1 (ML414)

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