上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mM*1mLinDMSO 5mg 10mg 50mg 100mg |
| CAS | 790702-57-7 |
| 别名 | N/A |
| 化学名 | N/A |
| 分子式 | C17H22N4O3S2 |
| 分子量 | 394.51 |
| 溶解度 | DMSO : 160 mg/mL (405.57 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
描述：
NGI-1 is a cell permeable inhibitor.
NGI-1 blocks EGFR N-linked glycosylation in lung adenocarcinoma cells as assessed. In controls EGFR is biotinylated, consistent with its plasma membrane expression, but in NGI-1 treated cells the EGFR is predominantly found in the non-biotinylated intracellular fraction suggesting a change in cellular localization[1].
[1]. Lopez-Sambrooks C, et al. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nat Chem Biol. 2016 Dec;12(12):1023-1030.
特别提醒：
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2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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