化学性质:
规格 | 5 mg 10 mg 25 mg 50 mg |
CAS | 179030-22-9 |
别名 | N/A |
化学名 | N/A |
分子式 | C8H13NO4S |
分子量 | 219.3 |
溶解度 | DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 5 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
描述:
NAG-thiazoline is an inhibitor of O-GlcNAcase (OGA; Ki = 180 nM).1 It is active against V. campbellii (MIC = 0.5 µM).2
1.Macauley, M.S., and Vocadlo, D.J.Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcaseBiochim. Biophys. Acta1800(2)107-121(2010) 2.Meekrathok, P., Stubbs, K.A., Aunkham, A., et al.NAG-thiazoline is a potent inhibitor of the Vibrio campbellii GH20 β-N-AcetylglucosaminidaseFEBS J.287(22)4982-4995(2020)
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