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N-3-hydroxydecanoyl-DL-Homoserine lactone is a bacterial quorum-sensing molecule.1 It activates SdiA (EC50 = 0.6 µM), a transcription factor that detects N-acyl homoserine lactones (AHLs), in the 14028/pJNS25 strain of S. enterica.2

1.Fekete, A., Frommberger, M., Rothballer, M., et al.Identification of bacterial N-acylhomoserine lactones (AHLs) with a combination of ultra-performance liquid chromatography (UPLC), ultra-high-resolution mass spectrometry, and in-situ biosensorsAnal. Bioanal. Chem.387455-467(2007) 2.Janssens, J.C.A., Metzger, K., Daniels, R., et al.Synthesis of N-acyl homoserine lactone analogues reveals strong activators of SdiA, the Salmonella enterica serovar Typhimurium LuxR homologueAppl. Environ. Microb.73(2)535-544(2007)

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