上海莼试生物技术有限公司
热卖产品最新促销最新推荐
抑制剂 > 微生物学和病毒学 > Helioxanthin derivative 5-4-2
产品名称:
Helioxanthin derivative 5-4-2
型号:
CS-01Y71894
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

5mg 10mg

CAS

203935-39-1

别名

 

化学名

10-(benzo[d][1,3]dioxol-5-yl)-9H-[1,3]dioxolo[4',5':3,4]benzo[1,2-f]isoindol-7-ol

分子式

C20H13NO5

分子量

347.32

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                            

Helioxanthin derivative 5-4-2, an analogue of helioxanthin (ACH126447), is a small-molecule inhibitor of HBV, HSV-1and HSV-2 virus with EC50 values of 0.08 μM, 0.29 μM and 0.16 μM, respectively [1].

Helioxanthin derivative 5-4-2 is a lactam and has been reported to inhibit the HBV DNA and RNA and viral protein expression [2]. Helioxanthin derivative 5-4-2 has significant anti-virus activity with EC50 values of 0.08 μM, 0.29 μM and 0.16 μM for HBV(hepatitis B virus), HSV-1(herpes simplex virus type 1) and HSV-2(herpes simplex virus type 2), respectively [1]. In addition, Helioxanthin derivative 5-4-2 inhibited HBV replication by post-transcriptional down-regulation of necessary transcription factors [3]. Helioxanthin derivative 5-4-2 has also exhibited potent anti-HCV (hepatitis C virus) activity with 55% inhibition at 1.0 μM and 80%inhibition at 3.0 μM [1].

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签:Helioxanthin derivative 5-4-2 

联系我们

联系人:高小姐

手    机:13585831301

Q      Q:3004967995

座    机:021-59541103

传    真:021-60443211

地    址:上海市嘉定区澄浏公路52号中科院技术转移中心24号楼