化学性质:
规格 | 250mg 500mg |
CAS | 351227-64-0 |
别名 | N/A |
化学名 | N/A |
分子式 | C23H20F2N5O5PS |
分子量 | 547.47 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Fosravuconazole is a prodrug of ravuconazole, with antifungal activity.
Fosravuconazole (BMS-379224) is a prodrug of ravuconazole, with antifungal activity[1].
Fosravuconazole (BMS-379224) is rapidly conversed to ravuconazole upon iv administration to rats. Fosravuconazole shows comparable efficacy at inhibiting C. albicans infection model in mice as orally administered ravuconazole[1].
[1]. Ueda Y, et al. Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: synthesis and biological properties. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3669-72.
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