化学性质:
| 规格 | 10mM*1mL in DMSO 5mg 10mg 50mg 100mg | 
| CAS | 174022-42-5 | 
| 别名 | N/A | 
| 化学名 | N/A | 
| 分子式 | C36H56O6 | 
| 分子量 | 584.83 | 
| 溶解度 | DMSO: ≥ 50 mg/mL (85.49 mM); H2O: < 0.1 mg/mL (insoluble) | 
| 储存条件 | Store at -20°C | 
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. | 
| Shipping Condition | Evaluation sample solution : ship with blue ice | 
产品描述:                                                                                                            
Bevirimat (PA-457; MPC-4326; YK FH312) is an anti-HIV drug derived from a betulinic acid-like compound; is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition.
[1]. Smith PF, et al. Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3',3'-dimethylsuccinyl)betulinic acid (bevirimat) against human immunodeficiency virus infection. Antimicrob Agents Chemother. 2007 Oct;51(10):3574-81. [2]. Salzwedel K, et al. Maturation inhibitors: a new therapeutic class targets the virus structure. AIDS Rev. 2007 Jul-Sep;9(3):162-72. [3]. Martin DE, et al. Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection. Antivir Chem Chemother. 2008;19(3):107-13.
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标签:Bevirimat
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