3′-deoxy ThymidineCS-01Y71533_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	25 mg 50 mg 100 mg 250 mg
CAS	5/5/3416
别名	N/A
化学名	N/A
分子式	C10H14N2O4
分子量	226.2
溶解度	DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 20 mg/ml
储存条件	-20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

3′-deoxy Thymidine is a nucleoside analog of thymidine that has antiviral activity.1 It inhibits HIV replication in infected human peripheral blood mononuclear cells (PBMCs; EC50 = 0.17 μM).2 3′-deoxy Thymidine (1, 3, 10, or 30 μM) reduces viral plaque formation in CV-1 cells infected with herpes simplex virus 1 (HSV-1).1

1.Waqar, M.A., Evans, M.J., Manly, K.F., et al.Effects of 2’,3’-dideoxynucleosides on mammalian cells and virusesJ. Cell. Physiol.121(2)402-408(1984) 2.Lin, T.-S., Schinazi, R.F., and Prusoff, W.H.Potent and selective in vitro activity of 3’-deoxythymidin-2’-ene (3’-deoxy-2’,3’-didehydrothymidine) against human immunodeficiency virusBiochem. Pharmacol.36(17)2713-2718(1987

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标签：3′-deoxy Thymidine

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