化学性质:
规格 | 10mM*1mLinDMSO 1mg 5mg 10mg |
CAS | 21802-37-9 |
别名 | N/A |
化学名 | N/A |
分子式 | C12H11N3O2 |
分子量 | 229.23 |
溶解度 | DMSO : 150 mg/mL (654.36 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Caerulomycin A (Cerulomycin) is a bipyridyl compound, induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases[1].
[1]. Gurram RK, et al. Caerulomycin A enhances transforming growth factor-β (TGF-β)-Smad3 protein signaling by suppressing interferon-γ (IFN-γ)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.
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