上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mM (in 1mL DMSO) 5mg 10mg 50mg 100mg |
| CAS | 955977-50-1 |
| 别名 |
|
| 化学名 | 4-(6-((4-(cyclopropylmethyl)piperazin-1-yl)methyl)-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin-4-yl)morpholine |
| 分子式 | C27H31FN6OS |
| 分子量 | 506.64 |
| 溶解度 | ≥ 22.7mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
PI-3065 is a small molecule and selective inhibitor of p110δkinase with an Ki value of 1.5nM and IC50 value of 5nM [1].
PI-3065 has been reported to selectively inhibit p110δkinase with Ki values of 15nM, 110nM, 130nM and 940nM, IC50 values of 5nM, 91nM, 600nM and >10000nM for p110δ, p110α, p110β and p110γ, respectively. In addition, PI-3065 has been revealed to inhibit 4T1 tumour growth and metastasis. PI-3065 has also noted to prolong survival and reduce the incidence of macroscopic metastases and other disease-associated pathologies [1].
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：PI-3065
联系人：高小姐
手 机：13585831301
Q Q：3004967995
座 机：021-59541103
传 真：021-60443211
地 址：上海嘉定区嘉罗公路1661
