化学性质:
规格 | 10mM*1mLinDMSO 5mg 10mg 50mg 100mg |
CAS | 207 |
别名 | N/A |
化学名 | N/A |
分子式 | C20H23N5O3S |
分子量 | 413.49 |
溶解度 | DMSO : ≥ 32 mg/mL (77.39 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
NU6300 is the first covalent ATP-competitive CDK2 inhibitor.IC50 value:Target: CDK2in vitro: NU6300 is a covalent CDK2 inhibitor that illustrates the potential of using vinyl sulfones to mediate irreversible inhibition. NU6300 blocks the inhibitor binding site. The effect was time dependent and relatively slow, with less than 50% reduction of the apparent binding capacity in 20 hr.
[1]. Anscombe E, et al. Identification and Characterization of an Irreversible Inhibitor of CDK2. Chem Biol. 2015 Sep 17;22(9):1159-1164.
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2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
标签:NU6300
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