化学性质:
规格 | 1 mg 5 mg 10 mg 25 mg |
CAS | 1246535-95-4 |
别名 | N/A |
化学名 | N/A |
分子式 | C16H20N8O |
分子量 | 340.4 |
溶解度 | Chloroform: 0.5mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
VS-5584 analog is a dual inhibitor of PI3Kα and mammalian target of rapamycin (mTOR; IC50s = 17 and 150 nM, respectively).1 It is a desmethyl analog of the dual PI3K/mTOR inhibitor VS-5584 .
1.Poulsen, A., Nagaraj, H., Lee, A., et al.Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602J. Chem. Inf. Model54(11)3238-3250(2014)
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