化学性质:
规格 | 10mM*1mL in DMSO 5mg 10mg 50mg |
CAS | 2 |
别名 | N/A |
化学名 | N/A |
分子式 | C10H12ClN5O2S |
分子量 | 301.75 |
溶解度 | DMSO: 125 mg/mL (414.25 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively[1].
[1]. Clare PM, et al. The cyclin-dependent kinases cdk2 and cdk5 act by a random, anticooperative kinetic mechanism. J Biol Chem. 2001 Dec 21;276(51):48292-9.
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