上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mM (in 1mL DMSO)10mg 25mg |
| CAS | 236392-56-6 |
| 别名 |
|
| 化学名 | [(E)-(3-aminopyridin-2-yl)methylideneamino]thiourea |
| 分子式 | C7H9N5S |
| 分子量 | 195.24 |
| 溶解度 | ≥ 83.3mg/mL in DMSO |
| 储存条件 | Store at -20° C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
Triapine is a potent inhibitor of ribonucleotide reductase activity with IC50 value of 1.6 μM for various of tumor cell lines [1].
Triapine has been reported to inhibit ribonucleotide reductase activity. Triapine has shown its antineoplastic activity by inhibiting DNA synthesis and repair. In addition, Triapine has been revealed to inhibit the growth of the murine M109 lung carcinoma and human A2780 ovarian carcinoma xenografts in nude mice. Moreover, Triapine was active against the L1210 leukemia over a broad range of dosages and was curative for the M109 lung carcinoma and human A2780 ovarian carcinoma xenograft mice. [1, 2]
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
标签：Triapine
联系人：高小姐
手 机：13585831301
Q Q：3004967995
座 机：021-59541103
传 真：021-60443211
地 址：上海市嘉定区澄浏公路52号中科院技术转移中心24号楼
