上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 50mg |
| CAS | 15826-37-6 |
| 别名 |
|
| 化学名 | disodium;5-[3-(2-carboxylato-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate |
| 分子式 | C23H14Na2O11 |
| 分子量 | 512.33 |
| 溶解度 | ≥ 5.12mg/mL in DMSO |
| 储存条件 | 4°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
Cromolyn sodium is an antiallergic drug. Cromolyn sodium is a GSK-3β inhibitor with an IC50 of 2.0 μM.
Cromolyn (sodium) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Pretreatment of IIR mice with Cromolyn (sodium) prior to ischemia exhibited no changes of ET-1 levels, injury score and inflammation (P>0.05, PreCr vs. M groups). In conclusion, administration of Cromolyn (sodium) after reperfusion, but not prior to ischemia, attenuates IIRI by downregulating ET-1 and suppressing sustained MC activation[1]. Cromolyn (sodium) has a role in the prevention of Chronic lung disease(CLD). Cromolyn (sodium) cannot be recommended for the prevention of CLD in preterm infants[2].
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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