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Cytidine 3’-monophosphate is a ribonucleotide.1 It is produced by hydrolysis of cytidine 2’,3’-cyclic monophosphate via RNase, which is inhibited by cytidine 3’-monophosphate, and can be dephosphorylated to cytidine by 3’-nucleotidase.2,3,4

1.Unemoto, T., Takahashi, F., and Hayashi, M.Relationship between the active sites of 2’,3’-cyclic phosphodiesterase with 3’-nucleotidase activity purified from Vibrio alginolyticusBiochim. Biophys. Acta185(1)134-142(1969) 2.Moussaoui, M., NoguÉs, M.V., Guasch, A., et al.The subsites structure of bovine pancreatic ribonuclease A accounts for the abnormal kinetic behavior with cytidine 2’,3’-cyclic phosphateJ. Biol. Chem.273(40)25565-25572(1998) 3.Kandeel, M., and Al-Taher, A.Metabolic drug targets of the cytosine metabolism pathways in the dromedary camel (Camelus dromedarius) and blood parasite Trypanosoma evansiTrop. Anim. Health Prod.52(6)3337-3358(2020) 4.Doucet, N., Jayasundera, T.B., Simonovi, M., et al.The crystal structure of ribonuclease A in complex with thymidine-3’-monophosphate provides further insight into ligand bindingProteins78(11)2459-2468(2010)

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