Aldehyde Reactive Probe (trifluoroacetate salt)CS-01Y70670

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一、概述：

化学性质：

规格	5mg 10mg 25mg 50mg
CAS	627090-10-2
别名	N/A
化学名	N/A
分子式	C12H21N5O4SCF3COOH
分子量	445.4
溶解度	DMF: 20 mg/ml,DMSO: 15 mg/ml,PBS (pH 7.2): 3 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA. ARP reacts with aldehyde groups formed when reactive oxygen species depurinate DNA, resulting in covalent linkage of biotin to these AP sites. The biotin-tagged DNA can then be detected using common avidin-conjugated reporters such as avidin-HRP. The ARP method is highly sensitive, enabling detection of 2.4 AP sites per 1x107 nucleotides of DNA.

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标签：Aldehyde Reactive Probe (trifluoroacetate salt)

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抑制剂 > DNA损伤/DNA修复 > Aldehyde Reactive Probe (trifluoroacetate salt)

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