化学性质:
规格 | 10mM*1 mL in DMSO 5 mg 10 mg 25 mg |
CAS | 395074-72-3 |
别名 | N/A |
化学名 | N/A |
分子式 | C21H22N4O2 |
分子量 | 362.42 |
溶解度 | DMSO : 100 mg/mL (275.92 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases[1].
GSK-3/CDK5/CDK2-IN-1 inhibits the phosphorylation of cdk5 peptide substrate phosphorylation, with an IC50 of less than about 50 μM[1].
[1]. Ahlijanian MK, et, al. Preparation of acylaminoimidazoles as inhibitors of cdk5, cdk2, and GSK-3. WO2002010141A1.
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