化学性质:
规格 | 1mg 5mg 10mg 25mg |
CAS | 1086639-59-9 |
别名 | FAK Inhibitor 10 |
化学名 | 1-(2-hydroxyethyl)-1,3,5,7-tetraazaadamantan-1-ium bromide |
分子式 | C8H17N4OBr |
分子量 | 265.15 |
溶解度 | 10mg/mL in DMSO, 0.3mg/mL in DMF |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over-expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397.[1] At 100 µM, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines.[1]
特别提醒:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
联系人:高小姐
手 机:13585831301
Q Q:3004967995
座 机:021-59541103
传 真:021-60443211
地 址:上海嘉定区嘉罗公路1661