Mutated EGFR-IN-1CS-01Y70209_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	10mM*1mL in DMSO 2mg 5mg 10mg 50mg 100mg
CAS	1421372-66-8
别名	N/A
化学名	N/A
分子式	C25H31N7O
分子量	445.56
溶解度	DMSO: ≥ 75 mg/mL (168.33 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.IC50 value:Target: Mutated EGFR inhibitorMore information can be found in Patent WO 2013014448 A1.2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer. EGFRL858R EGFRExon 19 deletion/T790M EGFRT790M

[1]. Patent WO 2013014448 A1. 2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer.

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1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：Mutated EGFR-IN-1

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抑制剂 > 酪氨酸激酶 > Mutated EGFR-IN-1

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