化学性质:
规格 | 1mg 5mg 10mg 20mg |
CAS | 936446-61-6 |
别名 | N/A |
化学名 | N/A |
分子式 | C24H26N4O3 |
分子量 | 418.49 |
溶解度 | DMSO: 250 mg/mL (597.39 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
NRC-2694 is an epidermal growth factor receptor (EGFR) antagonist with anti-cancer and anti-proliferative properties.
NRC-2694 at 80 ng (190 nm) concentrations causes comparable inhibition of EGFR expression[1].
In toxicity studies, the maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (po). NRC-2694 (10 mg/kg) regresses the tumor in mice[1].
[1]. Ramanadham Jyothi Prasad, et al. 6-7,dialkoxy quinazoline derivatives useful for treatment of cancer related disorders. US 8143250 B2
特别提醒:
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2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
标签:NRC-2694
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