上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 250mg 500mg |
| CAS | 854171-35-0 |
| 别名 | N/A |
| 化学名 | N/A |
| 分子式 | C20H19N3O4 |
| 分子量 | 365.38 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
E 804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R. IC50: 0.65 μM (IGF1R)[1].
Indirubin Derivative E804 is a water-soluble indirubin derivative as potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM. Indirubin Derivative E804 also inhibits CDK2/CycE with an EC50 of 0.23 μM[1].
[1]. Cheng X, et al. Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule. J Med Chem. 2017 Jun 22;60(12):4949-4962.
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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