化学性质:
规格 | 10 mg 50 mg 100 mg 250 mg |
CAS | 1210360-87-4 |
别名 | N/A |
化学名 | N/A |
分子式 | C11H9N3O3 |
分子量 | 231.2 |
溶解度 | DMF: insol,DMSO: 10 mg/ml,Ethanol: insol,PBS (pH 7.2): insol |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1 It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
1.Perez-Miller, S., Patek, M., Moutal, A., et al.In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike proteinbioRxiv308783(2020)
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标签:CAY10781
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