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Cinnamtannin B-1 is a proanthocyanidin polyphenol originally isolated from cinnamon bark that has antioxidant properties. Cinnamtannin B-1 has antioxidant properties in vitro, including inhibition of lipid peroxidation (IC50 = 2.25 μM). It also protects astrocytes and increases proliferation in an in vitro model of ischemia/reperfusion injury. In mice, it enhances migration of mesenchymal stem cells and improves wound healing. It exhibits COX-2 inhibition with 19, 27, and 86% inhibition in Sf9 cells at 10, 100, and 1,000 μg/ml, respectively.

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